Where Motherhood Can Be Possible

Dr. Louis R. Manara

Poor Ovarian Responders – Does Using The Natural Cycle Help?

 

A recently published Israeli study (Kedem et al., Fertility and Sterility – June 2014)  suggests that using the non-stimulated or minimally stimulated cycle for patients who are proven low responders in prior IVF cycles is not a sound strategy.


When IVF Fails: Exploring Reasons for Implantation Failure - Part 3

Jul 20, 2014 — by manara99
Tags: Repeat Ivf Failure Improving Ivf Success

In a previous communications we reviewed uterine causes for implantation failure, hydrosalpinges, egg quality, smoking, abnormal embryonic development, and embryo transfer technique.  When IVF fails to result in pregnancy in spite of repeated attempts, there are a number of additional explanations that must be considered. This communication explores the impact of lack of synchronization between embryonic and endometrial development, embryonic chromosomal abnormalities (aneuploidy), immunologic causes, and endometriosis as potential explanations for repeat IVF failure.


When IVF Fails: Exploring Reasons for Implantation Failure - Part 2

Jul 20, 2014 — by manara99
Tags: Repeat Ivf Failure Improving Ivf Success

In a previous communication we reviewed uterine causes for implantation failure.  When IVF fails to result in pregnancy in spite of repeated attempts, there are a number of non-uterine explanations that must be considered. This communication explores the impact of hydrosalpinges, egg quality, smoking, abnormal embryonic development, and embryo transfer technique on IVF success rates.


When IVF Fails: Exploring Reasons for Implantation Failure - Part 1

While in-vitro fertilization remains the most powerful treatment available to help infertile couples achieve pregnancy, the fact remains that it often fails. This communication is one of a series exploring various causes for repeat IVF/implantation failure. 


Will Losing Weight Improve Fertility?

May 19, 2014 — by manara99
Tags: Improved Infertility Care Weight And Fertility

Very few studies have looked at the impact of losing weight on fertility outcomes.  A recent study from Stanford University Medical Center suggests that weight loss of 10% or greater significantly improved the conception and live birth rates in overweight women.


Luteal Phase Defects – The Basics

May 5, 2014 — by manara99
Tags: Ovulation Disorders Luteal Phase Defects

Luteal phase defects have been described and written about in scientific journals for many years. Diagnosis has long been a source of controversy, while treatments are highly effective and relatively consistent from clinic to clinic.


Thyroid Function and Fertility

While extreme thyroid abnormalities are a well-known cause of infertility, minor thyroid abnormalities also clearly impact fertility and should be identified and treated.


Lifestyle And Diet Choices To Improve Fertility

Apr 16, 2014 — by manara99
Tags: Improving Fertility Healthy Pregnancy



Diet and lifestyle choices may have a significant impact on fertility.  A Harvard study conducted in 2007 concluded that women who had the highest fertility scores ate more monounsaturated fats, more high fiber carbohydrates, and had more iron in their diets from vegetable foods and supplements.


Low Sperm Counts – Some General Considerations

Apr 9, 2014 — by manara99
Tags: Male Infertility Ivf With Icsi

Semen analysis is an important part of the standard infertility evaluation.  In approximately 40-50 percent of infertility evaluations, an abnormality is found in the semen analysis.  Presented is a brief overview of the semen analysis including a discussion of clinical management of the infertile couple when the semen analysis is found to be abnormal.  Advances in assisted reproductive technologies in the past 20 years have made it possible to achieve excellent pregnancy rates even when sperm counts are extremely low. 


Frequently Asked Questions: “Why did my treatment fail?”

Mar 29, 2014 — by manara99
Tags: Understanding Infertility Treatment

It is not unusual for infertility treatments to fail, and when this happens, patients often ask the simple question, “Why did our treatment fail?” In order to provide a logical and accurate explanation, the clinician must take the time to provide the couple with important basic information concerning reproductive function and efficiency in humans.  An important fact to review during this dialogue is that the monthly chance of pregnancy in fertile couples (monthly fecundity) is 20%.  While various infertility treatments clearly improve the prospects for pregnancy, most do not achieve a 20% or higher chance of pregnancy in a given single month, with the notable exception of in-vitro-fertilization. 


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Dr. Louis R. Manara

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