Where Motherhood Can Be Possible

Dr. Louis R. Manara

Intrauterine Insemination Explained

The objective of intrauterine insemination (IUI) is to introduce a quantity of sperm into the female partner’s uterus, and thereby facilitate fertilization.  For IUI, sperm are first washed and placed in a sterile medium.  The sperm are then concentrated in a small volume of medium and are injected into the uterus.

Novel IVF Stimulation Protocol

Nov 27, 2014 — by manara99
Tags: Improving Ivf Success Improving Fertility Potential

One of the most important factors in achieving successful in-vitro fertilization is the ovarian stimulation.  Over the years, many stimulation protocols have been utilized in an attempt to achieve the  “ideal” controlled ovarian hyperstimulation protocol.  A recent publication in Fertility and Sterility, November 2015 presents an excellent protocol with some distinct advantages.

When Is Ovarian Stimulation With Intrauterine Insemination A Futile Treatment?


In the course of caring for infertile couples, various treatment options are often available.  Well-controlled randomized trials designed to evaluate treatment outcomes for specific groups of patients provide the data needed to counsel patients properly as to which treatment offers the best prognosis given their specific situation.  A study published in Fertility and Sterility in November 2014 from Harvard University provides important data concerning treatment with clomid or gonadotropin stimulation in conjunction with intrauterine insemination (IUI).  The study seeks to help identify patients who have poor treatment outcomes with ovarian stimulation in conjunction with intrauterine insemination. 

Premature Ovarian Failure – A Review

Nov 13, 2014 — by manara99
Tags: Infertility Anovulation Ovarian Failure

Premature ovarian failure (POF) is the loss of ovarian function before the age of 40.  Usually a woman’s ovaries supply eggs and hormones until the age of 51, which is the natural age of menopause.   However, with premature ovarian failure, complete loss of ovarian function can occur from the teenage years through age 40.  This condition is associated with infertility and often occurs before the traditional age of child bearing.

Successful IVF: How Important Is Endometrial Thickness?

Several publications have demonstrated that thin endometrial lining, as measured by transvaginal ultrasound, results in decreased prospects for successful embryonic implantation, while thicker endometrial development results in higher implantation rates.  A recent large study out of Shanghai Jiaotong University looked at the association between endometrial thickness and in-vitro fertilization outcomes in 2106 patients.  Patients with the thinnest endometria had the poorest outcomes.

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Dr. Louis R. Manara


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