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Dr. Louis R. Manara

Does Ovarian Stimulation For IVF Adversely Effect Embryo Implantation?

Oct 25, 2014 — by manara99
Tags: Improved Infertility Care Improved Ivf

It has long been suspected among clinicians that stimulation of the ovaries in standard IVF treatment creates an environment that is not ideal for embryo implantation.  A large study out of Duke University published in the August 2014 issue of Fertility and Sterility, compared pregnancy rates among donor egg cycles to IVF treatment cycles in which the intended mother used her own (autologous) eggs. In egg donor cycles there is no stimulation of the recipient's ovaries, while in autologous IVF cycles the ovaries are stimulated and the embryos are transferred later in that same cycle. Other studies have looked at this question by comparing fresh IVF treatment with frozen embryo transfer.  

Is it Time to Consider Chromosomal Analysis of All Embryos Before Embryo Transfer?

The quest to achieve the best possible outcomes with in-vitro fertilization has led to the use of embryo biopsy to determine the genetic makeup of an embryo before it is transferred to the uterus.  Performing embryo biopsies on the 5th day of embryonic life and application of new technologies that allow 24-chromosome evaluation, have led to improved outcomes.

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Dr. Louis R. Manara


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