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Accuracy of Early beta-HCG Levels in Predicting Fetal Viability By manara99 on May 30, 2013


An abstract presented at the April, 2013 meeting of the Pacific Coast Reproductive Society reviewed serial quantitative beta-HCG levels obtained every two days in the early first trimester of successfully treated infertility patients. They reviewed outcomes among more than 7000 pregnant patients in whom the quantitative beta-HCG level had failed to double on one or more occasions up to a total of 10,000 mIU/mL. Among those patients whose beta-HCG level failed to double at least once during monitoring, they found only one patient who continued to a viable pregnancy at 12 weeks of gestation.  They concluded that if even one beta-HCG level failed to double  properly over 48 hours up to levels of 10,000 mIU/mL, a woman rarely delivered a live baby.  The single patient in this study who had failure of the beta-HCG level to double, yet continued to a live birth, is evidence that it is still possible, though highly unlikely, that a live birth will be achieved in these circumstances.


This information is valuable for physicians counseling patients as to the likelihood of a successful pregnancy based on early information provided by serial quantitative beta-HCG levels.


Source: Pacific Coast Reproductive Society Meeting Abstracts, April 2013; Check, et. al.

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Dr. Louis R. Manara

Center for Reproductive Medicine and Fertility

Dr. Louis R. Manara and the Center for Reproductive Medicine and Fertility team are dedicated to helping families achieve parenthood through safe, versatile, and personalized treatment options. We are affiliated with several noteworthy organizations including:

  • American Society for Reproductive Medicine
  • Society for Assisted Reproductive Technology
  • American Osteopathic Association®

​If you are struggling with infertility, a professional diagnosis is the best way to explore your treatment options. Schedule your initial consultation today by contacting us online or calling us at (856) 767-0009.

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