

In-vitro
fertilization literally means fertilization of eggs outside of the
body. While originally intended for patients whose fallopian tubes
are absent or severely damaged, it has found application in couples
where the woman has endometriosis, or where infertility is "unexplained".
In addition, it is our most powerful treatment to overcome severe
male factor infertility and is commonly utilized for couples who have
tried all other treatment options unsuccessfully.
Most commonly patients
undergoing in-vitro fertilization undergo a month of preparation
of the ovaries termed down- regulation. This approach allows the
ovary to be stimulated with medications to mature multiple eggs.
Typically stimulations result in 5-15 eggs maturing so they may
be removed. At the appropriate time, the patient is given a light
anesthetic so that the eggs may be removed through a procedure which
allows the physician to see the ovaries with vaginal ultrasound
and "aspirate" the eggs by passing a needle directly into
the ovary, applying suction to remove the eggs. Once the eggs are
removed they are incubated with the partner's sperm and maintained
in an incubator for 3-5 days. At the end of this incubation, the
designated number of embryos is returned to the patient's uterus
through the cervix. This part of the process is painless and requires
no anesthesia. After the embryos are returned to the uterus, a pregnancy
test is done about 10-12 days later to determine if implantation
has occurred. Any embryos not returned to the woman's uterus may
be frozen for possible future transfer.
Success rates
for in-vitro fertilization vary according to the reason for the
procedure, as well as the patient's age. The "average"
patient can expect a 35% "take home baby rate" each time
she undergoes a cycle of in-vitro fertilization treatment.
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